Skin is a chemical, physical and immune shield that protects us against aggressions from our environment (light, pollution, temperature, pathogens, etc.), and prevents loss of body water. The hydric barrier function is mainly ensured by the semi-permeable stratum corneum and hydrolipidic film, while intercellular tight junctions seal epidermal cells to form an efficient physical barrier. In the event of barrier disruption, immunomodulatory factors and cells are recruited to form a secondary front-line defence.
In order to address the efficacy of dermo-cosmetic ingredients to modulate those different barrier aspects, StratiCELL has developed specific and adapted in vitro skin models and assays to drive your innovation.