DAMAGE RELATED TO LIGHT

StratiCELL offers evaluation of the effectiveness of active ingredients, formulations and finished products in protecting the skin against oxidative stress and molecular damages induced by different light rays.

Examples of assays performed at StratiCELL:

DNA damage

(8-oxo-2′-deoxyguanosine, cyclobutane pyrimidine dimers)

Oxidative stress response

(Heat Shock Proteins, Heme Oxygenase, Nrf-2 pathways)

Apoptosis

(p53 pathway, caspase-3 and sunburn cells morphology)

Inflammation

(Langerhans cells phenotype)

Protein oxidation

Elastin degradation