DAMAGE RELATED TO LIGHT

StratiCELL evaluates the efficacy of functional ingredients, formulations and finished products in protecting the skin against oxidative stress and molecular damages induced by different light rays.

Available endpoints:

DNA damages

(8-oxo-2′-deoxyguanosine, cyclobutane pyrimidine dimers)

Oxidative stress response

(SOD, Heme Oxygenase 1 and Nrf-2 pathways)

Apoptosis

(apoptotic caspase-3 and p53 factors, and sunburn cells morphology)

Inflammation

(Pro-inflammatory Interleukin)

Pigmentation

ExtraCellular Matrix modelling