INFLAMMATION

Skin inflammation is a complex process that comes in many forms, from occasional rashes, itching
and redness, to chronic conditions such as atopic eczema and psoriasis. StratiCELL has developed
a series of in vitro 2D and 3D models to study anti-inflammatory and calming actives.

Using functional 2D and 3D inflammatory skin models, StratiCELL reveals the efficacy and mechanisms of action of dermo-cosmetic actives aimed at reducing skin inflammation and increasing skin barrier resilience.

Examples of bioassays performed at StratiCELL:

Biomarkers of barrier resilience

(Filaggrin, Involucrin, Loricrin, Desmoglein, Keratin, etc.)

NFkB translocation/activation

(immunofluoresence staining or activity tests)

Morphological alterations

(such as spongiosis)

Cytokines and chemokines release

(IL-1a, IL-1ß, IL-6, IL-8, etc.)

Download our Inflammation brochure

Feel free to download our brochure to have more informations about Inflammation.