Oily skin is one of the most common dermatologic concerns. It is due to an excessive sebum production, called hyperseborrhea. Sebum is produced by differentiated sebocytes.

Our models

Sebocytes derived from human iPSC

3 phototypes: Causasian, Asian, African

Our tests

Sebocyte differentiation

immunofluorescence (Keratin 7, mucin 1) and quantification by RT-qPCR of key genes

Lipid production & accumulation

stimulating factors (testosterone, arachidic acid, linoleic acid), quantification of lipid storage (Nile Red staining)

5α-reductase activity (coming soon)

Examples of data