Senile lentigo or solar lentigines, also called age spots, are brown, grey or black spots located on the skin. They appear on areas of the body frequently exposed to the sun and are generally associated with skin ageing. Typical features of the lesion are an excessive proliferation of keratinocytes and production of melanin due to a disturbed release of growth factors.
StratiCELL has developed a unique in vitro 3D skin model of solar lentigines based on specific culture conditions to induce histological lesions similar to in vivo observations.
This model is a powerful tool for assessing the efficacy of compounds aimed at reducing age spots or improving their appearance.