Ageing is a complex and multi-factorial process that leads to deep changes in the skin structure and function. Discover the extensive range of assays offered by StratiCELL to explore cosmetic ingredients and formulations with anti-ageing properties, including functional tests and gene expression analysis.
StratiCELL evaluates the anti-oxidative effect of a compound by measuring its capacity :
StratiCELL evaluates the efficacy to modulate the ECM composition. Available efficacy tests include ECM structure, protein expression and enzymatic activities.
StratiCELL has developed a unique in vitro skin model of solar lentigines replicating hyperpigmented age spots. This unique in vitro skin model is a powerful tool for assessing the efficacy of compounds in reducing age spots.
Autophagy is a dynamic cell recycling process that improves the natural skin homeostasis. It has been long published that autophagy activators reboost and fortify the skin. Amongst all the available biomarkers, LC3 is the gold standard to study autophagy and the autophagic degradation flux.
To evaluate the anti-glycation potential of dermo-cosmetic compounds, StratiCELL provides a global approach combining both transcriptomic studies and various bioassays dedicated to addressing the molecular mechanisms and cellular processes involved in AGE stress.
BrdU (Bromodeoxyuridine)incorporation assay is a commonly used tool for measuring the influence of cosmetic ingredients on skin cell proliferation.
As we age, inflammatory events increase in the skin, accelerating sign of ageing.
In support to those functional studies or as a screening tool, StratiCELL has also designed a RT-qPCR TaqMan Low Density Array studying in a single step the expression of 93 genes playing key roles in dermal benefits.
The StratiCELL-BOX are cost-optimized packages of multiple in vitro efficacy assays ideally suited to accelerate the biological screening of multiple ingredients.
Discover now the Skin-Ageing-BOX and the Pollution-and-Light-Damage-BOX.
Feel free to download our brochure to have more informations.
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