Whether you are looking for skin whitening or a propigmenting effect, the 3D skin models from StratiCELL reproduce interactions observed in the epidermis and, if necessary, characteristics of pigmentation-related disorders.
Based on its proprietary melanized reconstructed human epidermis, StratiCELL has developed various 3D skin models, from light to dark skins.
Discover the efficacy of ingredients on pigmentation-related disorders using Solar Lentigines / Age Spots or Vitiligo 3D models.
Vitiligo is a complex pathology with imprecise origin. The activation of the immune system (cytotoxic action of CD8 T cells and secretion of cytokines by memory T lymphocytes) as well as a lack of adhesion of melanocytes seem to be at the source of melanocytorrhagy. StratiCELL offers a model of reconstructed human epidermis stimulated with various inflammatory cytokines in order to reproduce this typical condition observed in vitiligo.
StratiCELL has developed a unique in vitro reconstituted human epidermis model of solar lentigines based on specific culture conditions that reproduce individualized hyper-pigmentation spots. Given histological similarities to in vivo observations, this unique in vitro model is a powerful tool for assessing the efficacy of compounds in reducing age spots or improving their appearance.
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