The MicroBIOS Platform

In its MicroBIOS Platform, StratiCELL combines skin microbiota components and 3D reconstructed epidermis to study the efficacy of dermo-cosmetic ingredients on the cutaneous microbial flora.

The cutaneous microbial flora and its diversity is beneficial and even essential to maintaining a good skin health. In its MicroBIOS Platform, StratiCELL colonizes its reconstructed human epidermis with the major cutaneous microbial strains such as Staphylococcus aureus, Staphylococcus epidermidis, Cutibacterium acnes, or Malassezia furfur.

The MicroBIOS Platform allows StratiCELL to define the efficacy of dermo-cosmetic raw ingredients and formulated actives

to influence the growth of microorganisms,
and to influence the epidermal response to infection.

"Microbiome-Friendly" products

Microbiome-Friendly skin care products preserve the natural flora of the skin, including the commensal Staphylococcus epidermidis. Confirm the safetyness of your product by measuring its impact on the growth of S. epidermidis in the real context of an in vitro 3D reconstructed epidermis.

Technical Sheet

Anti-acne solutions

Acne is an inflammatory skin disease associated with an increase of Cutibacterium acnes phylotype IA1. C. acnes stimulates sebaceous gland, but also local keratinocytes, leading to a typical change in the expression of genes involved in the local inflammation, innate immunity and skin barrier.

Technical Sheet

Staphylococcus aureus colonization

StratiCELL evaluates the influence of ingredients on the adhesion and growth of Staphylococcus aureus in the real context of a 3D reconstructed epidermis. Inflammatory response of the tissue is evaluated at the gene and the protein levels. Anti-inflammatory efficay testing using the Atopic Dermatitis 3D model is also available at StratiCELL.

Malassezia overgrowth

Malassezia is a lipophilic natural cutaneous yeast. To allow new studies on the efficacy of innovative antifungal actives, StratiCELL has developed a 3D skin model of reconstructed epidermis colonized by Malassezia furfur.

Technical Sheet

To study the general response of skin to bacteria and yeasts colonization, StratiCELL offers a related transcriptomic tool based on the TaqMan Low Density Array technology. It allows to simultaneously analyze the expression of 93 genes palying key roles in the skin response to infections : inflammation, immune response and skin barrier modifications.

Download our MicroBIOS Platform brochure

Feel free to download our brochure to have more informations.

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The MicroBIOS Platform

Download our MicroBIOS Platform brochure

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