Acute inflammation in the skin is a response of the immune system to various triggers. In the skin, inflammation can occur following infection, sun-burn, allergen or contact with irritant. Compared to long-lasting chronic inflammation, this short-term immune response aims to rapidly counteract the source of dysfunction. Multiple cytokines and chemokines have been long described as relevant signatures of anti-inflammatory treatments. Based on those inflammatory biomarkers, StratiCELL has developed a range of assays to study the protective effects of compounds against acute inflammation induced by specific triggers such as UV radiation, TNF-alpha, phorbol myristate acetate (PMA), bacterial lipopolysaccharides (LPS) or lipopeptides (MALP-2).