ACUTE INFLAMMATION

Skin inflammation is a complex process that comes in many forms, from occasional rashes, itching
and redness, to chronic conditions such as atopic eczema and psoriasis. In order to study acute inflammation, StratiCELL has developed a series of in vitro 2D and 3D models and associated tests.

Acute inflammation in the skin is a response of the immune system to various triggers. In the skin, inflammation can occur following infection, sun-burn, allergen or contact with irritant. Compared to long-lasting chronic inflammation, this short-term immune response aims to rapidly counteract the source of dysfunction. Multiple cytokines and chemokines have been long described as relevant signatures of anti-inflammatory treatments. Based on those inflammatory biomarkers, StratiCELL has developed a range of assays to study the protective effects of compounds against acute inflammation induced by specific triggers such as UV radiation, TNF-alpha, phorbol myristate acetate (PMA), bacterial lipopolysaccharides (LPS) or lipopeptides (MALP-2).

Download our Acute inflammation brochure

Feel free to download our brochure to have more informations.