Skin is the first barrier against external aggressions, and is therefore the first target of many environmental stressors, such as solar irradiations and air pollutants. Those deleterious factors are correlated with skin ageing, inflammation and allergic reactions.

StratiCELL has developed a wide panel of functional and transcriptomic assays evaluating the protective and repairing effect of ingredients against pollution and light damages. 

Solar radiations and environmental pollutants are deleterious factors impacting the skin homeostasis. Prolonged cutaneous exposition to UV light and/or pollution results in accumulation of oxidized and damaged constitutive molecules, leading to overproduction of oxygen species (ROS), impairment in the extra-cellular matrix, critical DNA damages, and uncontrolled proinflammatory response. By eliminating photodamaged cells, apoptosis has an important function in the prevention of epidermal carcinogenesis. To evaluate the properties of skin care ingredients to repair or prevent from adverse events, StratiCELL has developed various functional assays to define:

  • protection against photodamaged DNA,
  • anti-inflammatory and anti-oxidative properties
  • detoxification

In support to those functional studies or as a screening tool, StratiCELL has also designed a TaqMan Low Density RT-qPCR 93 genes Array to study the expression of key genes involved in cell responses to pollution and light damages.

Download our Pollution&Light brochure

Feel free to download our brochure to have more informations.