Human Vaginal Epithelium, last publication in Personal Care Global
In line to a growing demand for non-animal in vitro alternatives for the safety testing of feminine and cosmetic care products, the present study describes the in-house reconstruction of a vaginal organoid tissue model and demonstrates its use to evaluate topical ingredients commonly found in feminine care formulations. The 3D Human Vaginal Epithelium (HVE) in vitro model reconstructed from isolated vulvar epithelial cells displayed in vivo-like structure and functionality from batch to batch, supporting its use as a reliable and reproducible in vitro tool to evaluate the safety and efficacy of intimate care ingredients and final products.