The MicroBIOS Platform

In its MicroBIOS Platform, StratiCELL combines skin microbiota components and 3D reconstructed epidermis to study the efficacy of active ingredients on the cutaneous microbial flora.

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The cutaneous flora and its diversity is beneficial and even essential to preserve an healthy skin. In its MicroBIOS Platform, StratiCELL colonizes its 3D reconstructed human epidermis with the major cutaneous microbial strains such as Staphylococcus aureus, Staphylococcus epidermidis, Cutibacterium acnes, or Malassezia furfur.

The MicroBIOS Platform allows StratiCELL to define the efficacy of active ingredients

  • to influence the growth of microorganisms,
  • and to influence the epidermal response to this infection3D

Microbiome-Friendly skin care products preserve the natural flora of the skin, including the commensal Staphylococcus epidermidis.

Confirm the safetyness of your active ingredient by measuring its impact on the growth of S. epidermidis in the real context of a 3D reconstructed human epidermis.

Technical Sheet

Acne is an inflammatory skin disease associated with an increase of Cutibacterium acnes phylotype IA1. C. acnes stimulates sebaceous gland, but also local keratinocytes, leading to a typical change in the expression of genes involved in the local inflammation, innate immunity and skin barrier. 

Technical Sheet

StratiCELL evaluates the influence of dermo-cosmetic active ingredients to modulate Staphylococcus aureus and Staphylococcus epidermidis using 3D
reconstructed human epidermis colonized by each strain, individually or in
combination.

Technical Sheet

Anti-inflammatory efficacy testing using the Atopic Dermatitis 3D model is also available at StratiCELL.

Malassezia is a lipophilic natural cutaneous yeast. To allow new studies on the efficacy of innovative antifungal actives, StratiCELL has developed a 3D skin model of reconstructed human epidermis colonized by Malassezia furfur.

Technical Sheet

To study the general response of skin to bacteria and yeasts colonization, StratiCELL offers a related transcriptomic tool based on the TaqMan Low Density Array technology. It allows to study the simultaneous expression of 93 genes palying key roles in the skin response to infections : inflammation, immune response and skin barrier modifications.

Download our MicroBIOS Platform brochure

Feel free to download our brochure to have more informations.

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