Malassezia furfur is a lipophilic natural cutaneous yeast, generally located in hyperseborrheic regions of the body, like face and neck. In case of dysbiosis, M. furfur is related to pityriasis versicolor or seborrheic dermatitis on the body skin. On human scalp, Malassezia overgrowth is however responsible for dandruff. To allow new studies on the efficacy of innovative antifungal actives, StratiCELL has overcame the challenging colonization of reconstructed epidermis by living M. furfur, as a model of Malassezia infection. This new in vitro model displays a huge reactivity of the tissue, as observed by the expression of inflammatory, immunity and skin barrier biomarkers.
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